Why studying sugars matters in the fight against Alzheimer’s disease

Two GlycoNet Investigators are using technology to better understand how sugars in the human body are connected to Alzheimer’s disease. Matthew Macauley and John Klassen, professors at the University of Alberta, are combining glycomics, the study of carbohydrates (sugars) and a mass spectrometer in a unique research project funded by GlycoNet. “If we can better understand the correlation between sugars and Alzheimer’s, then changing or altering the sugars could potentially alter the disease,” Macauley says.  Click here to read the full article.

Canada Excellence Research Chair (CERC) in Glycomics

The University of Alberta invites applications for the Canada Excellence Research Chair (CERC) in Glycomics. Established in 2008 by the Government of Canada, the CERC program supports world-renowned researchers and their teams to establish ambitious research programs at Canadian universities. The successful candidate will receive up to $20M over seven years to support an internationally-leading research program. The appointment will be in the Faculty of Science’s Department of Chemistry, which has 34 research faculty and 230 graduate students, supported by excellent services, including X-ray crystallography, mass spectrometry, and high-field NMR laboratories. Excellent electronic, machine, and glassblowing shops, and a biological…

Opportunity: AGC Administrative Assistant

Alberta Glycomics Centre
Competition No. - S104934740 Posting Date - Jan 19, 2018 Closing Date - Jan 26, 2018 Hourly Rate - $23.53 - $31.52 Grade - 06 Hours - 15 This part-time position has an end date one year from the date of hire with the possibility of extension. Regular hours of work will be 8 AM to 1 PM on Mondays, Tuesdays, and Wednesdays, but there is some flexibility with this schedule depending on the candidate's availability. The Alberta Glycomics Centre (AGC) is comprised of a team of highly motivated individuals whose research interests span a multidisciplinary array of biological processes…

AGC issues call for proposals for collaborative research projects

Alberta Glycomics Centre
Open Call for Applications The Alberta Glycomics Centre (www.glycomicscentre.ca) invites short applications from highly talented independent investigators (pre- and post-tenure) at universities in Alberta for consideration of affiliate membership positions in an internationally recognized research hub dedicated to translational carbohydrate chemistry and glycobiology. Of particular interest are applicants committed to working with other members of the Centre on interdisciplinary and innovative projects, ideally in the areas of human and animal health, agriculture, technology development, and bioengineering. Interested applicants are encouraged to contact one or more of the Centre’s principal investigators (PIs) to discuss possibilities for potential collaboration, and to develop…

Publication in Organic & Biomolecular Chemistry

Centre investigators Dr. Ratmir Derda, Dr. Todd Lowary, and Dr. John Klassen are among the collaborators on the following paper accepted for publication in Organic & Biomolecular Chemistry: "Genetically-encoded fragment-based (GE-FBD) discovery of glycopeptide ligands with differential selectivity for antibodies related to mycobacterial infections."

Cairo Research Group website goes live

As part of its ongoing commitment to support the researchers working as part of the Centre's internationally recognized research community, the AGC has partnered with BubbleUp web and marketing agency of Edmonton to upgrade not only its main website but also those of affiliated and associated lab groups. With the launch of the Cairo Research Group website on December 7th, the first phase of this enhancement has been completed. 2018 will see additional enhancements to the Centre's digital presence, as we continue to develop platforms and services that bring value to Alberta's research communities as well as to scientists from…

Klassen article on Human Milk Oligosaccharides accepted for publication

AGC Director Dr. John Klassen's article on "Screening Natural Libraries of Human Milk Oligosaccharides Against Lectins Using CaR-ESI-MS" has been accepted for publication in Analyst, the home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences published by the Royal Society of Chemistry.

Finding the right molecule in a haystack of life-saving possibilities

Developing a new drug starts with identifying the molecule or "ligand" that can block the molecular target or "receptor" involved in a disease. Even with high throughput screening, finding that one functional ligand for a receptor from a haystack of millions of possible compounds is expensive, high–risk and time–consuming. Converting a promising target into a commercial drug typically takes about 15 years and costs up to $800 million. To accelerate the discovery process, Canadian Glycomics Network (GlycoNet), in partnership with the Alberta Glycomics Centre (AGC) and the Derda Research Group at the University of Alberta (U of A), launched a…

Bennett Jones IP and Alberta Glycomics Centre: Innovation Vanguards

Bennett Jones is pleased to announce it is now providing intellectual property services to the Alberta Glycomics Centre. The Centre is home to some of the world’s most accomplished experts in carbohydrate-based research and is located at the University of Alberta. The focus of the Centre’s research is understanding the interactions of carbohydrates at the molecular level and applying the knowledge toward medical and commercial uses. These include projects designed to develop vaccines against tuberculosis, bloodstream infections in hospitalized patients, various cancers and Alzheimer’s disease. “The Alberta Glycomics Centre has been a leader in innovation and commercialization in Alberta and…